What it is...
Advances in medicine over the years have led to the development of new tests which detect disease, and treatments and therapies which improve recovery. It would not have been possible to do this work without access to samples of tissue and blood donated by patients with the disease.
Doctors and scientists working in the field of cardiovascular disease at The University of Manchester and partner hospitals within MAHSC have set-up a biobank to collect and store samples from donors with, or at risk of, specific cardiovascular conditions including genetic conditions. Samples are also linked to anonymised information (not personal data) about the donor’s condition.
The purpose of the Cardiovascular Diseases Biobank is to help biomedical research involved with preventing, diagnosing and treating cardiovascular disease. It will facilitate biomedical research within the MAHSC Cardiovascular Domain, Central Manchester University Hospitals NHS Foundation Trust, University Hospital South Manchester, The University of Manchester and the wider scientific community by providing high quality biomaterials to support the key cardiovascular research themes.
Samples and data held within the bank will be used by scientists to study in detail all conditions which are referred to as ‘cardiovascular disease’. This covers conditions affecting the heart and blood vessels; including the valves of the heart and problems with heart rhythm such as atrial fibrillation and Inherited Arrhythmia Syndromes.
What it means for patients: Provides an opportunity to volunteer to donate tissue or blood samples, some of which would otherwise be destroyed, so that it may be used in research into cardiovascular disease.
What it means for doctors and scientists: Provides access to a wide range of heart and vascular tissue for ethically approved research, fosters collaboration and accelerates the research process.
What it means for everyone: Leads to targeted treatments or cures for cardiovascular conditions available in the nearer future.
The Cardiovascular Diseases Biobank will act as custodian of the samples it holds and will release them only to individuals or organisations, both in the UK and abroad; that have an acceptable scientific background and work to the highest ethical standards. Samples will not be used for non-medical or non-scientific purposes.
Who is involved?
MAHSC links six NHS Trusts in Manchester with The University of Manchester to form Europe’s largest clinical academic campus, which translates research discoveries into patient benefits. As part of this, the Cardiovascular Diseases Biobank aims to help researchers by providing access to large numbers of tissue and blood samples from people with cardiovascular disease.
Central Manchester University Hospitals NHS Foundation Trust and University Hospital South Manchester NHS Foundation Trust have a large specialist and tertiary referral service in cardiology and cardiac and vascular surgery, with potential to obtain donation of an extensive range of cardiac and vascular tissue. They are ideally placed to deliver a specific cardiovascular diseases biobank and will include samples collected on a ‘project-specific’ basis, tailored to the individual needs of the researcher.
The Cardiovascular Diseases Biobank is housed in a secure, dedicated bio-banking facility at Manchester Royal Infirmary.
For more information contact Dr Jay Brown, Biobank Manager.