Spectroscopic grading system for prostate cancer diagnosis
Professor Peter Gardener of The University of Manchester’s School of Chemical Engineering and Analytical Science was teamed with clinicians at The Christie NHS Foundation Trust and Salford Royal NHS Foundation Trust through MIMIT to develop a novel way of improving biopsy testing in cases of suspected prostate cancer.
His team has created a spectroscopic grading system, which will aid pathologists conducting biopsy screenings via a traffic light system: cancer-free, suspicious, or cancer detected.
Currently, the identification of cancer cells within biopsy tissue is a subjective process and relies on the judgement of the pathologist. Adoption of this technology will reduce bias and help professionals to make more accurate decisions.
A real-time analysis system has also been created to improve the efficiency of the process, with the intent of reducing the stressful period of time in which a patient needs to wait to hear news on their condition.
The team is working with six industry collaborators as well as partners both in the UK and internationally to take the grading system into clinical environments where it can begin to improve patient outcomes.
It has leveraged £935,000 in funding, including through the Williamson Trust and EPSRC, £25,000 in proof-of-principle funding from UMIP, and has led to numerous conference appearances and high-impact publications. Two post-doctorates and four PhDs have also been awarded during the process of the development.